The primary difference between Drip and ActiveDEMAND is the level and depth of automation they provide. While both services offer basic automation tools, Drip is focused exclusively on email marketing and automation, while ActiveDEMAND takes a broader approach and offers a range of marketing automation tools and features. Drip also features a built-in CRM system and powerful segmentation features that make it easy to target specific users. ActiveDEMAND offers more integrated reporting tools, sales automation features, and customizable campaign templates, allowing users to automate more complex marketing operations. Ultimately, the choice between Drip and ActiveDEMAND will depend on the individual business needs.