Mailshake is an email marketing platform that is designed to help businesses streamline and automate their outreach efforts. It offers features such as email templates, scheduling, and personalization to help users efficiently send personalized emails to their prospects and clients. On the other hand, Zoho is a CRM platform that provides a comprehensive set of tools for managing customer relationships. It offers features like lead management, sales forecasting, and customer segmentation to help businesses track and analyze the performance of their sales and marketing activities. In summary, while Mailshake focuses primarily on email marketing, Zoho offers a wider range of features that can help businesses manage their sales and marketing processes more effectively.